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Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa
| dc.contributor.author | Patiño Cano, Laura Patricia | |
| dc.contributor.author | Quintana Manfredi, Rodrigo | |
| dc.contributor.author | Pérez, Miriam | |
| dc.contributor.author | García, Mónica | |
| dc.contributor.author | Blustein, Guillermo | |
| dc.contributor.author | Cordeiro, Ralf | |
| dc.contributor.author | Pérez, Carlos D. | |
| dc.contributor.author | Schejter, Laura | |
| dc.contributor.author | Palermo, Jorge A. | |
| dc.date.accessioned | 2019-09-10T13:32:13Z | |
| dc.date.available | 2019-09-10T13:32:13Z | |
| dc.date.issued | 2017 | |
| dc.identifier.other | DOI: 10.1002/cbdv.201700425 | |
| dc.identifier.uri | http://jadimike.unachi.ac.pa/handle/123456789/125 | |
| dc.description | Three azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at 343 m. Besides linderazulene (1), and the known ketolactone 2, a new brominated C16 linderazulene derivative (3) was also identified. This compound has an extra carbon atom at C(7) of the linderazulene framework. The antifouling activity of compounds 1 and 2 was assayed in the laboratory with Artemia salina larvae, and also in field tests, by incorporation in soluble-matrix experimental antifouling paints. The results obtained after a 45 days field trial of the paints, showed that compounds 1 and 2 displayed good antifouling potencies against a wide array of organisms. Compound 3, a benzylic bromide, was unstable and for this reason was not submitted to bioassays. Two known cembranolides: pukalide and epoxypukalide, were also identified as minor components of the extract. | es_ES |
| dc.description.abstract | Three azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at 343 m. Besides linderazulene (1), and the known ketolactone 2, a new brominated C16 linderazulene derivative (3) was also identified. This compound has an extra carbon atom at C(7) of the linderazulene framework. The antifouling activity of compounds 1 and 2 was assayed in the laboratory with Artemia salina larvae, and also in field tests, by incorporation in soluble-matrix experimental antifouling paints. The results obtained after a 45 days field trial of the paints, showed that compounds 1 and 2 displayed good antifouling potencies against a wide array of organisms. Compound 3, a benzylic bromide, was unstable and for this reason was not submitted to bioassays. Two known cembranolides: pukalide and epoxypukalide, were also identified as minor components of the extract. | es_ES |
| dc.language | eng | |
| dc.language.iso | en | es_ES |
| dc.relation | none | |
| dc.relation.ispartofseries | Chemistry & Biodiversity; | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | octocorals | es_ES |
| dc.subject | Acanthogorgiidae | es_ES |
| dc.subject | marine natural products | es_ES |
| dc.subject | azulene sesquiterpenoids | es_ES |
| dc.subject | antifouling activity | es_ES |
| dc.title | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.type | info:eu-repo/semantics/publishedVersion |
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